HrabiKot *PL (Monkey) looking for new home

Monkey is looking for a new home, she does not like when our other cat are using the litter box so she keeps peeing outside the box. Hopefully she will stop with this when she has her own box.

Monkey is a very calm Devon and she loves laying outside on the balcony and sunbath the whole day.
She is neutered and had never had any kittens due to  luxating patella, she walks a bit funny sometimes and shakes her back leg to get the patella in place.
We have been to the veterinary two times just to make sure she does not have any pain or issues with it. They say there is nothing to do but she does not suffer from it.

Let me know if you are interested in giving Monkey a home.

Monkey to the left, Cookie to the right.

Kittens 14 Weeks

Now the kittens are 14 weeks.
Sally and Ruby is available.

Maggie May (Pinky)

Ruby Tuesday

Sally Maclennane

Kitten Sad news

Kitten 2, Pinky did not make it :'(
She had trouble with not the finding a nipple to nurse and when we put her to one she started sucking but let go quite quickly and did not find it again. We had to put her on several times to try to convince her to suck.
I tried to bottle feed her but with no great success she still did not want to suck the milk. This morning she seemed better as soon as we put her to a nipple she started sucking with out any fuss. But later in the day she was getting much worse.
We went to the veterinarian and she got an injections with vitamins and fluid. But this evening she left us. A very sad day.  We only knew Pinky for a short while but she already made a great impression. Big kisses we miss you <3

Kittens!!

Yesterday  S*Exaduz Divine Kynareth gave birth to 5 kittens

1,  Weight 80g Tabby,

2, Kitten weight 83g White

3,  Weight 76g White, Girl

 4, Weight 81g, White, Girl

5, Weight 76g, White, Girl

Kynareth expecting

Only about 11 days left to it is time.

 

HCM scan

Yesterday Baloo and Xoxo were at Blue Oasis Veterinary Clinic and scanned the heart  for HCM,
 Everything was normal.

DNA result for the boys

 FedraRex*PL Baloo

Agouti: A/A 
Point 1: carrier (Siamese)
Blood type: b/b
Cinnamon: carrier
Dilute: carrier

PKD -/- negative (PKD1 see text below)

DevonDream*PL Yarglee
Point 1: +/+ Siamese
Blood type: A/b

PKD -/- negative














I got a bit concerned when I saw that both the boys had markers in 2 places for longhair!!
But i fond out that if a cat have markers on Longhair4 and 4_2 they are shorthair but carrier.
Puuh.. I have been looking suspiciously on Baloos fluffy tail all morning... but I did not need to worry :)



http://www.abyssiniancats.info/abyblog/tag/longhair-in-cats/

Tag Archive for Longhair in Cats

Controversial DNA test results?

Christine Ruessheim | July 16, 2011 | No comments

There was recently a huge discussion about the test results for an “Aby” whose DNA sample has been sent to two labs (UC Davis and Texas A & M) for screening if the cat carries for longhair since only 10 years ago some Somalis were introduced in that pedigree. The results came back different or should I say inconclusive. Read my thoughts about it below.
I will be trying to explain with different words and  how the explanatory text from the Texas A&M site can be interpreted and whose correct link, btw, is:
http://www.catdnatest.org/DNA-results.html .
First thing to notice is, that apparently Texas A&M (other than UC Davis) only tests for 3 of the 4 Mutations involved in modifying hair length in cats. They are M1, M2 and M4, hence they do not test for M3. Also the Texas A & M uses two different markers for M4 (M4 and M4_2), due to difficulties in typing they say. Their observance in results is, that in most cases the result is the same for both markers (for example M4 +/- and M4_2 +/-). In order for a cat to show the longhair however it seems that cats need to have two mutations at either M4 or M4_2 (or both together?). One mutation at each marker of M4 would not make it a longhair cat, unless there would be an additional mutation at one of the other loci (M1- M3). So the compound heterozygote doesn’t apply for mutation M4 when both markers have one mutation.
Below you can see a couple of combinations of different mutations and how they “translate”:

Mutation M1	Mutation M2	Mutation M3	Mutation M4	Mutation M4_2	Phenotype	Genotype
+/-	+/-	-/-	-/-	-/-	longhair	compound heterozygote
-/-	-/-	+/-	+/-	-/-	longhair	compound heterozygote
-/-	-/-	-/-	+/+	-/-	longhair	homozygote
-/-	-/-	+/-	-/-	-/-	shorthair	carrying M3
-/-	-/-	-/-	+/-	+/-	shorthair	carrying M4/M4_2
-/-	-/-	-/-	-/-	-/-	shorthair	homozygote
-/-	-/-	+/-	+/-	-/-	longhair	compound heterozygote

The test result for the cat in questions shows one mutation for M4_2, and no mutation for M4. Cat also doesn’t have any mutation for M1 and M2, M3 is not tested by that Laboratory. Another Laboratory reported the cat to be free of any mutation (M1-M4), but I do not know wether they test for both markers in M4.  So far, it is not clear, whether mutation M4_2 is functional or not. None of the description I read so far did state that anywhere clearly, neither pro nor con. If there do exist cats which tested M4_2 +/+ and are phenotypically longhaired, then the answer should be yes. Question is, did they also test M4 +/+, if so, it still would not be clear if the mutation M4 at the 2nd marker is functional or not. My first approach would be to contact Texas A&M and ask them exactly that question. Maybe, they are inconclusive themselves, then we are back to square.


PKD1

PKD1 (Polycystic Kidney Disease) in Felines

Polycystic Kidney Disease (PKD) is a well documented abnormality in domestic cats. Cystic kidneys can sporadically occur in any population of cats. PKD is not a new disease and has been reported in the literature for over 30 years. The heritable form of PKD1 may not have initially occurred in Persians as a new mutation, but perhaps in random bred cats. Unfortunately, PKD1 does not have a strong clinical presentation. The presentation of PKD1 is similar to one of the most common causes of death for any cat, renal failure. Thus, PKD1 has gone unnoticed for many years and has spread throughout the Persian breed. Any breed that has used Persians in their foundation or propagation should have concerns for PKD1.
In Persians, the condition has been shown to be inherited as a single autosomal dominant gene. It is estimated over 37% of Persians have PKD1, a breed that accounts for nearly 80% of the cat fancy. Many lines and catteries have been able to greatly reduce this frequency by using ultrasound screening methods and improved breeding practices

I do not know how common it have been to use Persians in the breeding program for Devon Rex and if the longhair gene we see today are only coming from breeding them together, if that is the case I believe it is a good idea to also do the DNA test for PKD1 the lab does the test from the same swab so there is no extra steps to take.